For Research Use Only. Not for human or veterinary use.
ACE-031 is listed for legitimate laboratory and research procurement. This 99%+ research-use product is available in 1 listed specification. Review product codes, storage guidance and COA status, then request a wholesale quotation. Batch documentation is available on request.
Volume discounts are available for larger purchasing plans. Please contact us for a quotation.
Delivery includedUsually within 7 days after dispatch
Quality resolutionRefund or replacement when approved
24/7 contactWholesale assistance on WhatsApp
Product profile
About ACE-031
ACE-031 is a recombinant fusion protein composed of the extracellular domain of the activin type IIB receptor (ActRIIB) linked to the Fc portion of a human antibody. It acts as a potent "ligand trap," binding with high affinity to myostatin (GDF-8) and other related TGF-β superfamily members, such as Activin A and GDF-11. By sequestering these negative regulators of muscle growth, ACE-031 effectively blocks their signaling pathways, thereby removing the "brake" on muscle protein synthesis and promoting significant skeletal muscle hypertrophy.
Main functions
1.Significant Increase in Muscle Mass: By inhibiting myostatin, it removes the primary constraint on muscle growth, leading to substantial increases in lean body mass observed in preclinical and early-stage clinical studies.
2.Improved Muscle Function: The increase in muscle mass is associated with potential gains in muscle strength and physical performance.
3.Potential Metabolic Benefits: Early research suggests that increasing muscle mass may positively influence overall energy metabolism and insulin sensitivity.
4.Long-Acting Profile: As a fusion protein, it possesses a prolonged half-life, allowing for less frequent dosing, such as every 2-4 weeks.
5.Targets Core Pathway: It directly intervenes in the central negative regulatory mechanism of muscle atrophy, offering a novel approach for muscle-wasting conditions.
Recommended audience
Patients with muscle-wasting diseases, such as muscular dystrophy, cancer cachexia, or sarcopenia.
High-level athletes or bodybuilders seeking to overcome genetic limitations for substantial muscle hypertrophy.
Individuals suffering from severe muscle loss due to aging, prolonged bed rest, or rehabilitation, who need to reverse muscle atrophy.
Order formatOne box accepted
QuotationConfirmed on WhatsApp
DeliveryShipping and duties included
DocumentationPublished COA or available on request
Research product specification
Product information
ACE-031 is listed for legitimate laboratory and research procurement. This 99%+ research-use product is available in 1 listed specification. Review product codes, storage guidance and COA status, then request a wholesale quotation. Batch documentation is available on request.
Handling information
Storage guidance
Keep unopened lyophilized products protected from light and moisture; store at 2-8°C short term or -20°C long term. After reconstitution, refrigerate according to product documentation and minimize freeze-thaw cycles.
Customer-first resolution
Report quality concerns within 14 days of delivery
Contact us with the order number, batch details and available photos. Opened products are accepted for review. When a quality claim is approved, you may choose a full refund or replacement shipment.
