FOR RESEARCH USE ONLY · NOT FOR HUMAN OR VETERINARY USE
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Research product specification

ET10

Epithalon

For Research Use Only. Not for human or veterinary use.

Epithalon is listed for legitimate laboratory and research procurement. This 99%+ research-use product is available in 2 listed specifications. Review product codes, storage guidance and COA status, then request a wholesale quotation. Batch documentation is available on request.

Listed purity
99%+
Availability
Available for inquiry
Select specification10mg x 10vials

COA available on request

COACOA available on request

Volume discounts are available for larger purchasing plans. Please contact us for a quotation.

Delivery includedUsually within 7 days after dispatch

Quality resolutionRefund or replacement when approved

24/7 contactWholesale assistance on WhatsApp

Product profile

About Epithalon

Epithalon (also known as Epitalon or Epithalamin) is a synthetic tetrapeptide (sequence: Ala-Glu-Asp-Gly, AEDG) designed based on the amino acid composition of Epithalamin, a polypeptide extract derived from the bovine pineal gland. As a research peptide compound, Epithalon is most notable for its potential as a telomerase activator. In vitro studies have demonstrated that it can activate telomerase enzymatic activity by upregulating the expression of the human telomerase reverse transcriptase (hTERT) gene, thereby extending telomere length. Telomere length is considered a biomarker of cellular aging, which has generated significant interest in Epithalon within the fields of healthy aging and longevity research.

Main functions

  • "1.Activates Telomerase and Extends Telomeres: Research confirms that Epithalon treatment induces telomerase activity and significantly extends telomere length. In normal human cells (e.g., epithelial cells and fibroblasts), this is primarily achieved through upregulation of hTERT expression; in certain cancer cells, it can also occur via the Alternative Lengthening of Telomeres (ALT) mechanism. Animal studies have shown lifespan extension of up to 12.3%–13.9% in mice.
  • 2.Slows Age-Related Functional Decline: In aged rhesus monkeys, Epithalon has been observed to restore circadian rhythms of melatonin and cortisol production. It also improves age-related estrous function decline in female mice and reduces the frequency of chromosome aberrations in bone marrow cells.
  • 3.Improves Glucose Metabolism: In aged female rhesus monkeys, Epithalon has been shown to correct age-related declines in glucose tolerance and restore dynamic insulin responses to glucose loading.
  • 4.Potential Tumor Suppression Properties: In a transgenic mouse model of breast cancer, Epithalon significantly inhibited tumor development, with maximum tumor volume reduced by 33% compared to controls, and suppressed HER-2/neu oncogene expression.
  • 5.Protection in Retinal Inflammatory Conditions: In a rat model of hereditary retinitis pigmentosa, Epithalon helped preserve retinal morphological structure and improved its bioelectrical activity."

Recommended audience

  • "Health-conscious individuals focused on healthy aging and longevity, seeking to slow the aging process at the cellular level.
  • Researchers studying telomere biology, telomerase regulation, and anti-aging drug development.
  • Preclinical investigators exploring peptide bioregulators in age-related metabolic disorders such as glucose intolerance.
  • "
Order formatOne box accepted
QuotationConfirmed on WhatsApp
DeliveryShipping and duties included
DocumentationPublished COA or available on request

Research product specification

Product information

Epithalon is listed for legitimate laboratory and research procurement. This 99%+ research-use product is available in 2 listed specifications. Review product codes, storage guidance and COA status, then request a wholesale quotation. Batch documentation is available on request.

Handling information

Storage guidance

Keep unopened lyophilized products protected from light and moisture; store at 2-8°C short term or -20°C long term. After reconstitution, refrigerate according to product documentation and minimize freeze-thaw cycles.

Customer-first resolution

Report quality concerns within 14 days of delivery

Contact us with the order number, batch details and available photos. Opened products are accepted for review. When a quality claim is approved, you may choose a full refund or replacement shipment.