YZFyzfpeptide.comSS-31 (Bendavia / Elamipretide)10mgFor Research Use Only
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Research product specification
2S10
SS-31 (Bendavia / Elamipretide)
For Research Use Only. Not for human or veterinary use.
SS-31 (Bendavia / Elamipretide) is listed for legitimate laboratory and research procurement. This 99%+ research-use product is available in 2 listed specifications. Review product codes, storage guidance and COA status, then request a wholesale quotation. Published COA documentation is available for selected specifications.
Volume discounts are available for larger purchasing plans. Please contact us for a quotation.
Delivery includedUsually within 7 days after dispatch
Quality resolutionRefund or replacement when approved
24/7 contactWholesale assistance on WhatsApp
Product profile
About SS-31 (Bendavia / Elamipretide)
SS-31 (also known as Elamipretide, MTP-131, or Bendavia) is a synthetic tetrapeptide (sequence: H-D-Arg-Dmt-Lys-Phe-NH₂) belonging to the Szeto-Schiller (SS) peptide family. It is uniquely characterized by its ability to selectively target the inner mitochondrial membrane through high-affinity binding to cardiolipin, achieving over 1,000-fold mitochondrial enrichment independent of membrane potential. This precise targeting mechanism stabilizes mitochondrial membrane structure, reduces reactive oxygen species (ROS) production, enhances ATP synthesis, and inhibits mitochondrial permeability transition pore (mPTP) opening. Based on its broad mitochondrial protective effects, SS-31 has demonstrated therapeutic potential in various disease models associated with mitochondrial dysfunction. Notably, SS-31 (Elamipretide) has recently received accelerated FDA approval as the first treatment for Barth syndrome.
Main functions
1.Protects and Stabilizes Mitochondrial Function: By binding to cardiolipin, it maintains cristae structural integrity, preserves electron transport chain function, and significantly enhances ATP production while reducing mitochondrial ROS generation across multiple models.
2.Reverses Age-Related Energetic Decline: In aged animal models, a single dose restores skeletal muscle mitochondrial ATP production capacity, oxidative phosphorylation efficiency (P/O), and cellular energy status (PCr/ATP) to youthful levels within one hour, while improving exercise endurance.
3.Potent Anti-Inflammatory and Neuroprotective Effects: By inhibiting the NF-κB pathway, downregulating pro-inflammatory cytokines (TNF-α, IL-1β), and promoting ATG5-dependent autophagy, SS-31 exerts protective effects in neurodegenerative disease models including spinal cord injury and Parkinson's disease.
4.Improves Age-Related Organ Function: Reverses diastolic dysfunction in cardiac aging models; protects ovarian follicle units via NRF2/HO-1 pathway activation in ovarian aging; and prevents and reverses visual acuity decline in visual aging models.
5.Expanding Clinical Indications: Supported by preclinical and clinical studies for conditions associated with oxidative stress and mitochondrial dysfunction, including ischemia-reperfusion injury, heart failure, insulin resistance, and cardiomyopathy.
Recommended audience
SS-31 (also known as elamipretide, MTP-131, or Bendavia) is a synthetic tetrapeptide (sequence: H-D-Arg-Dmt-Lys-Phe-NH₂) belonging to the Szeto-Schiller (SS) peptide family. It is uniquely capable of highly selective targeting of the inner mitochondrial membrane; by binding to the key phospholipid cardiolipin, it achieves more than 1,000-fold enrichment within the mitochondria, independent of membrane potential. This precise targeting mechanism enables it to effectively stabilize mitochondrial membrane structure, reduce reactive oxygen species (ROS) production, enhance ATP synthesis efficiency, and inhibit the opening of the mitochondrial permeability transition pore (mPTP). Given its broad mitochondrial protective effects, SS-31 has demonstrated therapeutic potential in various disease models associated with mitochondrial dysfunction. Notably, SS-31 (elamipretide) recently received accelerated approval from the U.S. FDA, becoming the first drug indicated for the treatment of Barth syndrome.
Order formatOne box accepted
QuotationConfirmed on WhatsApp
DeliveryShipping and duties included
DocumentationPublished COA or available on request
Research product specification
Product information
SS-31 (Bendavia / Elamipretide) is listed for legitimate laboratory and research procurement. This 99%+ research-use product is available in 2 listed specifications. Review product codes, storage guidance and COA status, then request a wholesale quotation. Published COA documentation is available for selected specifications.
Handling information
Storage guidance
Keep unopened lyophilized products protected from light and moisture; store at 2-8°C short term or -20°C long term. After reconstitution, refrigerate according to product documentation and minimize freeze-thaw cycles.
Customer-first resolution
Report quality concerns within 14 days of delivery
Contact us with the order number, batch details and available photos. Opened products are accepted for review. When a quality claim is approved, you may choose a full refund or replacement shipment.
